Download here the PDF Programme
Day 1: Thursday, October 17th 2024
| 09:00 - 10:00 | Registration | |
| 10:00 - 10:15 | Opening | |
| 10:15 - 13:30 | SESSION 1 | |
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Singlet oxygen mediated precision modification of G4 and IM nucleic acids Annemieke Madder (invited speaker) |
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PLGA Polymeric Nanoparticles for the Enhancement of Cytotoxicity and Cellular Uptake of 5-fluoro-2’-deoxyuridine Oligomers Santiago Grijalvo |
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Synthesis of ethidium-based G-quadruplex ligands as potential antiparasitic agents Juan Camilo Cardozo-Muñoz |
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| 11:30 - 12:15 | Coffee break | |
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The Role of Cations in the Intrinsic Photostability of DNA Marco Marazzi |
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RNase H-sensitive multifunctional ASO-based constructs as promising tools for the treatment of multifactorial complex pathologies Ariadna Vila-Planas |
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A triplex structure to understand TINA stabilizing effect Miguel Garavís |
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Phenanthroline-based multifunctional metalo-organics as potential therapeutics: G4 selective ligands and beyond Ana Gómez-Bra |
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Hybridization properties of bis-pyrimidine clamps: Understanding the role of 2-sugar and 5-methyl-pyrimidine modifications on triplex stability Arnau Domínguez |
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| 13:30 - 15:00 | RANN XIII Group Picture & Lunch | |
| 15:00 - 18:00 | SESSION 2 | |
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Sustainable methods for oligonucleotide synthesis Masad J. Dahma |
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Advanced DNA-based Nanostructures with Metal Ions Miguel A. Galindo |
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Exploring skeletal diversity through a thymine nucleoside Ana San-Félix |
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DNA G Quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease Pablo Peñalver |
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The use of (CTT)n oligonucleotides to reverse frataxin silencing in Friedreich Ataxia Juan Alberto López García |
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16:30 - 17:00 |
Coffee break | |
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Structural Characterization of the 3' Untranslated Region of the SARS-CoV-2 RNA Genome Sergio López-Nuñez |
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Polypurine Reverse Hoogsteen Oligonucleotides as a Therapeutic Tool against SARS-CoV-2 Carlos J. Ciudad |
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Targeting Telomeric G-quadruplex using Supramolecular Strategies Jorge González-García |
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Structural Analysis of the Programmed Ribosomal Frameshift RNA Element of Sarbecoviruses: A Target for Antiviral Drug Discovery Gurudutt Dubey |
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| 18:00 - 18:30 | Discussion and election of the site for RANN XIV | |
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21:00 - 23:00 |
Conference dinner (sponsored by ChemGenes) Hosteria del Estudiante C/ Colegios, 3 28801 Alcalá de Henares |
Day 2: Friday, October 18th 2024
| 09:00 - 13:00 | SESSION 3 | |
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Quadruplexes are everywhere! Jean-Louis Mergny (invited speaker) |
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Chemometrics applied to the study of i-motif DNA structures Raimundo Gargallo |
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Aptamer-Drug Conjugates for a Targeted and Synergistic Anticancer Response: Exploiting T30923-5-fluoro-2’-deoxyuridine (INT-FdU) Derivatives Daniela Benigno |
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ParmBSC2: Development of an Improved Atomistic Force Field for Nucleic Acids Milosz Wieczór |
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G-quadruplex ligands based on pyrvinium as potential antiparasitic and antibiotic drugs Belén García-Pérez |
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Development of TRIFAPYs as cationic lipid-based systems for efficient nucleic acids transfection in eukaryotic cells Ana Delgado |
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| 11:00 - 11:45 | Coffee break | |
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Adapting DNA-based nanostructures to yield hybrid carriers for drug delivery purposes Silvia Hernandez-Ainsa |
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Development of RNA-targeted small-molecule agents against SARS-CoV-2 Sergi Chumillas |
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Non G-tetrads and i-motifs: a marriage of convenience Bartomeu Mir |
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Regulating long non-coding RNAs for Pancreatic Cancer treatment Irene Pardo |
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Naphthalene diimide derivatives as G-quadruplex ligands with potent antiparasitic activity Manuel Pérez-Soto |
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| 13:00 - 14:30 | RANN XIII Group Picture & Lunch | |
| 14:30 - 16:15 | SESSION 4 | |
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Xanthine nucleosides and their analogues in higher order structures Lajos Kovács |
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RNA Guanine Quadruplex and SARS-CoV Unique Domain: Understanding their Interaction Cristina García-Iriepa |
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Assessment of the interaction to G4s, nucleotides and drugs of novel G4 supramolecular binders María Amparo Lopo-March |
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Exploiting the therapeutic potential of microRNAs and DNA nanotechnology to address cardiac disease Marina Ripalda-Paredes |
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Presence and bioactivity of microRNAs in non-conventional biomasses. Potential of mass spectrometry for their study Miriam Guzmán-Lorite |
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| 16:00 - 16:15 | Closing remarks and farewell |
